VCFS includes many common features: Other common findings include minor learning problems and speech and feeding problems. Velocardiofacial syndrome is the most common syndrome associated with a cleft palate. It is estimated that one in 2, to 5, children per year are born with velocardiofacial syndrome, and more thanindividuals in the United States have this syndrome.
What is Cleft Lip? The lip forms between the fourth and seventh weeks of pregnancy. As a baby develops during pregnancy, body tissue and special cells from each side of the head grow toward the center of the face and join together to make the face. This joining of tissue forms the facial features, like the lips and mouth.
A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This results in an opening in the upper lip.
The opening in the lip can be a small slit or it can be a large opening that goes through the lip into the nose. A cleft lip can be on one or both sides of the lip or in the middle of the lip, which occurs very rarely. Children with a cleft lip also can have a cleft palate.
What is Cleft Palate? The roof of the mouth palate is formed between the sixth and ninth weeks of pregnancy. A cleft palate happens if the tissue that makes up the roof of the mouth does not join together completely during pregnancy. For some babies, both the front and back parts of the palate are open.
For other babies, only part of the palate is open. Other Problems Children with a cleft lip with or without a cleft palate or a cleft palate alone often have problems with feeding and speaking clearly and can have ear infections. They also might have hearing problems and problems with their teeth.
Joshua's Story Joshua was born with cleft lip and palate. Some children have a cleft lip or cleft palate because of changes in their genes. Cleft lip and cleft palate are thought to be caused by a combination of genes and other factors, such as things the mother comes in contact with in her environment, or what the mother eats or drinks, or certain medications she uses during pregnancy.
Like the many families of children with birth defects, CDC wants to find out what causes them. Understanding the factors that are more common among babies with a birth defect will help us learn more about the causes. Recently, CDC reported on important findings from research studies about some factors that increase the chance of having a baby with an orofacial cleft: If you are pregnant or thinking about becoming pregnant, talk with your doctor about ways to increase your chances of having a healthy baby.
Diagnosis Orofacial clefts, especially cleft lip with or without cleft palate, can be diagnosed during pregnancy by a routine ultrasound. They can also be diagnosed after the baby is born, especially cleft palate. However, sometimes certain types of cleft palate for example, submucous cleft palate and bifid uvula might not be diagnosed until later in life.
Surgery to repair a cleft lip usually occurs in the first few months of life and is recommended within the first 12 months of life. Surgery to repair a cleft palate is recommended within the first 18 months of life or earlier if possible.
Children born with orofacial clefts might need other types of treatments and services, such as special dental or orthodontic care or speech therapy. These teams usually consist of experienced and qualified physicians and health care providers from different specialties. Cleft and craniofacial teams and centers are located throughout the United States and other countries.Prehistoric art tells historians that people once thought congenital diseases, or birth defects, werebad omens or the displeasing of the gods.
In one instance, it was thought that cleft lip was caused by themother of the baby being startled by a rabbit. Odd as it may seem, at that time it w. US Orofacial Cleft Statistics. Overall, the United States’ most common congenital condition remains Down syndrome, a group of associated characteristics caused by an abnormal duplication of the 21st chromosome.
cleft lip and cleft palate occur more frequently in male children, although females are more likely to be born with isolated. The first association study of cleft lip with or without cleft palate (CL/P), with candidate genes, found an association with the transforming growth-factor alpha (TGFA) locus.
This finding has since been replicated, in whole or in part, in three independent studies. Occurrence. CDC recently estimated that, each year in the United States, about 2, babies are born with a cleft palate and 4, babies are born with a cleft lip with or without a cleft palate.
1 Isolated orofacial clefts, or clefts that occur with no other major birth defects, are one of the most common types of birth defects in the United States.
1 . In recent years, Down syndrome has become more common, and children with Down syndrome are living longer. Read below for recent statistics on Down syndrome in the United States. Down syndrome continues to be the most common chromosomal disorder.
. Nonsyndromic cleft lip and palate is a complex genetic disorder with variable phenotype, largely attributed to the interactions of the environment and multiple genes, each potentially having certain effects.